From NAMI (National Alliance on Mental Illness)

Research Study Trying to Improve Depressive Symptoms Quickly

Several medications are effective for treating depression; however, they take weeks or months to achieve their full effects. NIMH (the National Institute of Mental Health) is studying whether a drug can cause a rapid antidepressant effect in patients with bipolar or unipolar depression. The study also tries to see if it can sustain the results with another medication in certain patients. Understanding how this works may help us understand depression and design better antidepressants. NIMH is seeking people ages 18-65 with depression (unipolar or bipolar) who are:

  • Free of other serious medical conditions
  • Willing to participate in a minimum of a 12-day inpatient stay

Research medications provided free of charge. Compensation and transportation reimbursement is provided.

Atendemos pacientes de habla hispana.

Call: Libby Jolkovsky, M.S. at 301-402-9347 or 1-877-MINDNIH (1-877-646-3644),; for other studies:


Do you AND a family member have DEPRESSION?

Please consider taking part in a nationwide research study — Genetics of Recurrent Early-Onset Depression, sponsored by the National Institute of Mental Health.

You may be able to participate if:
– You’ve had 2 or more periods of depression.
– The first depression started before age 31.
– At least one brother, sister or parent has also had depression.
– We are unable to include people with bipolar disorder, or with bipolar disorder in the immediate family.

For more information: contact our National Coordinating Center at Stanford University. All emails & calls are strictly confidential. or call toll-free (877) 407-9529

Or, contact a participating university:
Columbia University: or call (212) 543-6297
Howard University: or call (202) 806-7642
Johns Hopkins University: or call (410) 614-1017
University of Iowa: or call (888) 850-8531
Rush University Medical Center (Chicago): or call (888) 820-3395
Stanford University: or call (650) 736-0481 or (650) 723-3258

Solving the Genetics of Major Depression

This study will create a DNA collection from over 2,000 people to permit scientists to search for depression-related genes. These scientists will not be given any information that could identify you or your family.

Benefits of Participating
– Help us with this difficult task.
– Finding relevant genes could lead to the development of better treatments.
– You receive reimbursement for participation.

If you volunteer
– You will be interviewed about your personal and family mental health history.
– You do not need to live near our sites. Interviews can be completed by phone.
– You will be asked for a blood specimen for DNA studies.
– You may be asked for help in inviting family members to participate, but family participation is not required.
– Confidentiality is protected.

Do genes cause depression?

Studies of depression in families suggest that around 50% of the predisposition to major depression is caused by genes. People with recurrent depression that starts at a younger age have more relatives with depression. There are probably many interacting genes, rather than a single gene as in some medical disorders.

Why find these genes?

Identifying these genes would help us to understand the brain mechanisms involved in severe depression. This could lead to discovery of new treatments.

For more information, go to:

Severe Depression Study

Feeling sad and depressed? Losing pleasure in engaging in daily activities? Difficulty concentrating or easily distracted? Suffering from low self-worth? If you or someone you know is experiencing any of these symptoms, you may be suffering from Severe Depression. Daniel D. Anderson, M.D., is conducting a research study for people with Severe Depression. If you qualify, you may be eligible to participate in a study testing the effectiveness of a research medication for the treatment of Severe Depression at no cost to you. If you would like additional information regarding this study and are between the ages of 18 and 75, please contact the office of Daniel D. Anderson, M.D., at (310) 891-0106.

The Depression Research Clinic at Stanford University

The Stanford University Depression Research Clinic in the Department of Psychiatry and Behavioral Sciences is currently conducting several studies evaluating the effectiveness of new and investigational treatments for depression. If you are bothered by depression nearly every day, are 18 years or older, in good physical health, and are able to attend weekly appointments at Stanford between the hours of 8 a.m. and 5 p.m., Monday through Friday, you may be eligible. All of the studies involve an initial phone screen, during which time research staff will ask you questions to determine eligibility, explain the studies for which you may be eligible, and answer any questions that you may have. Participation is free and all calls are confidential. If you would like more information, please call the research study line at 650-723-8330

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