According to a new study in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM), some women taking SSRI’s may experience what they call a delayed secretory activation. This means they are inhibited from complete milk secretion.

“The breasts are serotonin-regulated glands, meaning the breasts’ ability to secrete milk at the right time is closely related to the body’s production and regulation of the hormone serotonin,” said Nelson Horseman, PhD, of the University of Cincinnati and co-author of the study. “Common antidepressant drugs like fluoxetine, sertraline and paroxetine are known as selective serotonin reuptake inhibitor (SSRI) drugs and while they can affect mood, emotion and sleep they may also impact serotonin regulation in the breast, placing new mothers at greater risk of a delay in the establishment of a full milk supply.”

I am not aware that this has been a problem in our experience at the PPSC, but it’s important information to have on hand, particularly if women experience difficulty in this area.

Reference: The Endocrine Society (2010, February 1). Common antidepressant drugs linked to lactation difficulties in moms. ScienceDaily.

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