New study on treatment of “Postpartum Depression with Psychotic Features” April 2010 issue of The American Journal of Psychiatry emphasizes that caution must be taken when using antidepressants during the postpartum period for woman with psychotic depression, even in the absence of hypomanic symptoms. They also state that psychotic depression within 4 weeks postpartum should be diagnosed as bipolar depression, whether or not there are hypomanic symptoms.

Women in the study were diagnosed with major depression with psychotic features and treated with mood stabilizers and antipsychotic medication. The authors worry that using antidepressants can sometimes put women at risk for acute exacerbation of symptoms and must be used cautiously.

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